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Related Experiment Videos

Sympathetic skin response: age effect

V E Drory1, A D Korczyn

  • 1Department of Neurology, Tel-Aviv Medical Center, Israel.

Neurology
|September 1, 1993
PubMed
Summary
This summary is machine-generated.

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Sympathetic skin response is present in younger adults but declines with age. Elderly individuals show reduced response in lower limbs (50%) and upper limbs (73%), with decreased amplitude.

Area of Science:

  • Neuroscience
  • Gerontology

Background:

  • The sympathetic skin response (SSR) is a non-invasive measure of sympathetic nervous system function.
  • Age-related changes in autonomic function are common but require further elucidation.

Purpose of the Study:

  • To investigate age-related alterations in sympathetic skin response (SSR) in healthy individuals.
  • To quantify the prevalence and amplitude of SSR in different age groups.

Main Methods:

  • Recruitment of 100 healthy participants across a wide age range (20-91 years).
  • Assessment of sympathetic skin response (SSR) in both upper and lower limbs.
  • Statistical analysis to determine the relationship between age and SSR parameters.

Main Results:

Related Experiment Videos

  • Sympathetic skin response (SSR) was universally present in younger subjects.
  • Prevalence of SSR in the elderly was reduced: 50% in lower limbs and 73% in upper limbs.
  • A significant decline in SSR amplitude was observed with increasing age in both limb types.

    • Conclusions:

    • Sympathetic nervous system function, as measured by SSR, significantly diminishes with advancing age.
    • Age-related decline in SSR may indicate reduced sympathetic innervation or altered response mechanisms in the elderly.
    • These findings highlight the impact of aging on autonomic nervous system regulation.