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Myelitis following chickenpox: a case report

J Rosenfeld¹, C L Taylor, S W Atlas

¹Department of Neurology, University of Pennsylvania Hospital, Philadelphia 19104-4283.

|September 1, 1993

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Primary varicella infection in an 18-year-old woman caused myelopathy and spinal MRI abnormalities. Treatment with steroids and acyclovir led to clinical and radiological improvement.

Area of Science:

Neurology
Infectious Diseases
Radiology

Background:

Varicella zoster virus (VZV) infections are common, but neurological complications are rare.
Myelopathy, a condition affecting the spinal cord, can occur secondary to VZV reactivation.

Observation:

An 18-year-old female presented with acute myelopathic symptoms and a T-8 sensory deficit.
Cervical and thoracic spinal cord MRI revealed significant abnormalities, indicative of inflammation or ischemia.

Findings:

The patient experienced a primary varicella infection.
Clinical symptoms and MRI findings demonstrated improvement following treatment with corticosteroids and intravenous acyclovir.

Implications:

This case highlights a rare neurological complication of primary varicella infection.

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Prompt diagnosis and treatment with antiviral therapy and steroids can lead to favorable outcomes in VZV-associated myelopathy.