Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple organ failure

B Eiseman, R Beart, L Norton

    Surgery, Gynecology & Obstetrics
    |March 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    This study defines multiple organ failure (MOF) in critically ill patients. High mortality rates and significant costs highlight the need for further research into this complex clinical syndrome.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Extracorporeal Assist - Liver, Spleen, and Lung.

    Scandinavian journal of gastroenterology·2016
    Same author

    Rapid decompression: a protective substance.

    Project report. USAF School of Aviation Medicine·2014
    Same author

    Combat casualty management for tomorrow's battlefield: urban terrorism.

    The Journal of trauma·2001
    Same author

    Fifty years at the Forum.

    Bulletin of the American College of Surgeons·2001
    Same author

    Feasibility of damage control surgery in the management of military combat casualties.

    Archives of surgery (Chicago, Ill. : 1960)·2000
    Same author

    Dose-response trial of megestrol acetate in advanced breast cancer: cancer and leukemia group B phase III study 8741.

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology·1999
    Same journal

    THE USE OF COMBINED PRESERVATION TECHNIQUES FOR EXTENDED STORAGE OF ORTHOTOPIC LIVER HOMOGRAFTS.

    Surgery, gynecology & obstetrics·2010
    Same journal

    The Role of Electrical Pacemakers in the Treatment of Unexpected Cardiac Arrest.

    Surgery, gynecology & obstetrics·2010
    Same journal

    Colonic and proctoscopic diseases.

    Surgery, gynecology & obstetrics·2010
    Same journal

    A summary of the surgical aspects of certain sulfonamides and antibiotic agents.

    Surgery, gynecology & obstetrics·2010
    Same journal

    Penetrating cranial wounds; a summary of methods used in management; collective review.

    Surgery, gynecology & obstetrics·2010
    Same journal

    The use of compression in the treatment of injuries.

    Surgery, gynecology & obstetrics·2010
    See all related articles

    Area of Science:

    • Critical Care Medicine
    • Intensive Care
    • Surgical Outcomes

    Background:

    • Multiple organ failure (MOF) is a complex clinical syndrome affecting critically ill patients.
    • Patients often require mechanical and pharmacological support for survival.
    • Understanding MOF is crucial due to its significant impact on patient outcomes and healthcare resources.

    Purpose of the Study:

    • To characterize the syndrome of multiple organ failure (MOF) in postoperative patients.
    • To identify the primary etiologies and contributing factors of MOF.
    • To establish a foundational dataset for future research on MOF.

    Main Methods:

    • Retrospective analysis of 42 postoperative patients with failure of two or more vital organ systems.
    • Identification of initial hospitalization triggers (trauma, bleeding).

    Related Experiment Videos

  • Assessment of the role of sepsis and clinical management complications in MOF etiology.

    • Main Results:

    • A high mortality rate of 69% was observed in the studied patient cohort.
    • The mean duration of multiple organ failure was 30.5 days.
    • Sepsis was a significant etiological factor in 69% of cases, with clinical management complications contributing in 57%.

    Conclusions:

    • Multiple organ failure (MOF) represents a critical clinical challenge with high mortality.
    • Etiological factors include trauma, bleeding, sepsis, and clinical management complications.
    • There is a compelling need for a large, statistically valid database to address the scientific and social implications of MOF.