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Neonatal and infant heart transplantation
1Children's Memorial Hospital, Chicago, Illinois.
Pediatric Clinics of North America
|October 1, 1993
Summary
Cardiac transplantation is now a viable option for neonates with congenital heart disease. This review covers the key aspects of heart transplants for infants, including indications and management.
Area of Science:
- Pediatric Cardiology
- Cardiovascular Surgery
- Neonatal Medicine
Background:
- Cyclosporine A has enabled routine cardiac transplantation for pediatric cardiomyopathy.
- Cardiac transplantation is increasingly considered for neonates with severe structural congenital heart disease.
Purpose of the Study:
- To review the indications for cardiac transplantation in neonates and infants.
- To outline the pretransplant evaluation process for this population.
- To describe the post-transplant management strategies for neonates and infants.
Main Methods:
- Literature review of cardiac transplantation in neonates and infants.
- Synthesis of current guidelines and clinical practices.
- Analysis of outcomes and management protocols.
Main Results:
- Established indications for neonatal cardiac transplantation.
- Detailed pretransplant workup protocols.
- Comprehensive post-transplant care guidelines.
Conclusions:
- Cardiac transplantation is a critical treatment for select neonates with congenital heart disease.
- Careful patient selection and multidisciplinary management are essential for successful outcomes.
- Ongoing research is vital to further refine transplant protocols for infants.