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Related Experiment Videos

Heparin vs. saline for peripheral i.v. locks in children

C Kleiber, K Hanrahan, C L Fagan

    Pediatric Nursing
    |July 1, 1993
    PubMed
    Summary

    Saline flushes are as effective as heparin for maintaining pediatric peripheral intravenous locks. This study found no significant difference in complications or duration between the two methods in children over 28 days old.

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    Area of Science:

    • Pediatric Nursing
    • Intravenous Therapy
    • Pharmacology

    Background:

    • Maintaining patency of peripheral intravenous (IV) locks is crucial in pediatric care.
    • Heparin flush solution is commonly used, but saline is a potential alternative.
    • Evidence comparing saline and heparin efficacy in pediatric populations is limited.

    Purpose of the Study:

    • To compare the efficacy of saline versus heparin flush solutions.
    • To determine the best method for maintaining peripheral IV lock patency in pediatric patients.

    Main Methods:

    • Prospective, randomized, double-blind study design.
    • 124 pediatric patients (infants >28 days and children) with peripheral IVs.
    • IVs were flushed with either saline or heparinized saline.

    Main Results:

    • No significant difference in the total duration of IV use between groups.
    • Comparable incidence of complications (e.g., occlusion, phlebitis) between saline and heparin groups.
    • Saline demonstrated equivalent efficacy in maintaining IV lock patency.

    Conclusions:

    • Saline is an effective and safe alternative to heparin for flushing peripheral IV locks in pediatric patients over 28 days of age.
    • Saline flushes can be confidently used to maintain pediatric peripheral IV patency.
    • Further research may explore cost-effectiveness and long-term outcomes.

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