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Updated: Jul 30, 2026

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats
Published on: April 28, 2023
[Pathogenetic rationale for the treatment of obesity]
Abstract:
On the basis of experience gained in prolonged follow-up of 1095 obese patients, studies of their hormonal homeostasis using computer-aided cluster analysis the author comes to a conclusion that division of obesity cases into constitutional exogenous and hypothalamic is conditional. The hypothalamic syndrome develops in 100% of obesity cases. A course of pathogenetic therapy paralleled by a subcaloric diet and exercise therapy is suggested. Bitemporal inductothermy proved to be effective. The new complex for obesity treatment includes low-caloric diets combined with pathogenetic drug therapy and physiotherapeutic exposure of the mid-brain.
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