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Molecular analysis of the microtubule motor dynein
1Cell Biology Group, Worcester Foundation for Experimental Biology, Shrewsbury, MA 01545.
Abstract:
Dynein is a large enzyme complex that has been found in recent years to be responsible for a variety of forms of intracellular movement associated with microtubules. Molecular analysis of several of the polypeptide components of dynein and a related complex has provided important new insight into their structural organization and mechanism of action in the cell.