Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Epididymal sarcoidosis

D M Ryan1, B A Lesser, L A Crumley

  • 1Department of Medicine, Wayne State University, Grace Hospital, Detroit, Michigan 48235.

The Journal of Urology
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Respiratory disease in pregnancy.

BJA education·2025
Same author

Asthma Exacerbations Requiring ICU: Risk Factors and Challenges in Management.

Irish medical journal·2025
Same author

An unexpected role for a Wnt-inhibitor: Dickkopf-1 triggers a novel cancer survival mechanism through modulation of aldehyde-dehydrogenase-1 activity.

Cell death & disease·2014
Same author

Uptake, distribution and immunotoxicological effects of mercury in mice.

Environmental monitoring and assessment·2013
Same author

Compact inline optical electron polarimeter.

The Review of scientific instruments·2013
Same author

Comparative persistence and adherence to overactive bladder medications in patients with and without diabetes.

International journal of clinical practice·2012

Sarcoidosis rarely affects the genitourinary tract, with only 28 documented cases of epididymal involvement. This study presents two new cases, highlighting the importance of considering sarcoidosis in testicular lesion diagnoses.

Area of Science:

  • Urology
  • Pathology
  • Immunology

Background:

  • Sarcoidosis is a multisystem inflammatory disease of unknown etiology.
  • Genitourinary involvement is rare, with limited reported cases of epididymal sarcoidosis.
  • Differential diagnosis of testicular lesions typically includes infections, neoplasms, and other inflammatory conditions.

Observation:

  • Two cases of histologically confirmed epididymal sarcoidosis are presented.
  • Case 1: A 27-year-old asymptomatic male with multiple scrotal nodules.
  • Case 2: A 34-year-old male with a history of sarcoidosis diagnosed via transbronchial biopsy, who later developed a testicular mass.

Findings:

  • Surgical exploration revealed noncaseating granulomatous inflammation in both patients, consistent with sarcoidosis.

Related Experiment Videos

  • Histopathological examination confirmed sarcoidosis as the cause of epididymal lesions.
  • The findings underscore the potential for sarcoidosis to manifest in the epididymis, even in asymptomatic individuals.

    • Implications:

    • Sarcoidosis should be included in the differential diagnosis for patients presenting with testicular or scrotal masses.
    • Increased awareness may lead to earlier diagnosis and appropriate management of genitourinary sarcoidosis.
    • Further research is warranted to understand the pathogenesis and optimal treatment strategies for epididymal sarcoidosis.