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Duodenogastric reflux quantification in peptic ulcer surgery: comparison between different surgical techniques
P Parrilla1, J A Lujan, R Robles
1Department of General Surgery, Virgen de la Arrixaca, University Hospital, University of Murcia, El Palmar, Spain.
Surgery
|January 1, 1993
Summary
Gastric surgery significantly increases duodenogastric reflux, especially after resection. Bile acid levels strongly correlate with reflux, measured using technetium 99m-labeled hepatoiminodiacetic acid (99mTc-HIDA).
Area of Science:
- Gastroenterology
- Nuclear Medicine
- Surgical Oncology
Background:
- Duodenogastric reflux (DGR) is a common complication after gastric surgery.
- Quantifying DGR is crucial for understanding post-surgical complications.
Purpose of the Study:
- To quantify DGR in patients with various gastric surgery types.
- To compare DGR rates between surgical and control groups.
- To correlate DGR with bile acid levels.
Main Methods:
- Utilized 6-hour intravenous infusion of technetium 99m-labeled hepatoiminodiacetic acid (99mTc-HIDA).
- Quantified 99mTc-HIDA in gastric juice.
- Studied 50 post-gastric surgery patients and 10 healthy controls.
Main Results:
- Gastric surgery patients exhibited significantly higher DGR than controls (p < 0.001).
- Resected patients showed higher reflux rates compared to non-resected patients (p < 0.001).
- A strong correlation was found between 99mTc-HIDA and bile acid concentrations (p < 0.001).
Conclusions:
- Gastric surgery leads to significantly increased duodenogastric reflux.
- Resection procedures are associated with higher reflux rates.
- 99mTc-HIDA is a reliable marker for quantifying DGR and correlates with bile acid levels.