Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prognosis after syncope: impact of left ventricular function

H R Middlekauff1, W G Stevenson, L A Saxon

  • 1Department of Medicine, University of California, School of Medicine, Los Angeles 90024-1679.

American Heart Journal
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effect of sunlight on the initiation of sexual activity in ranch mink.

Canadian journal of comparative medicine and veterinary science·2010
Same author

Pregnant mares' urine as a source of oestrogens.

Canadian journal of comparative medicine and veterinary science·2010
Same author

The concentration penicillin in fore milk following intramammary infusion for the treatment of mastitis.

Canadian journal of comparative medicine and veterinary science·2010
Same author

Injury as a cause of mastitis.

Canadian journal of comparative medicine and veterinary science·2010
Same author

Gonadotrophic hormone therapy in dairy practice.

Canadian journal of comparative medicine and veterinary science·2010
Same author

The decreased oxygen uptake during progressive exercise in ischemia-induced heart failure is due to reduced cardiac output rate.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas·2006

Left ventricular dysfunction significantly increases sudden death risk in cardiac syncope patients. This finding is crucial for risk stratification and guiding treatment in syncope evaluation.

Area of Science:

  • Cardiology
  • Electrophysiology

Background:

  • Cardiac syncope is linked to sudden death risk, while unexplained syncope is generally benign.
  • Left ventricular dysfunction can reduce diagnostic accuracy and treatment efficacy in syncope patients.
  • Previous studies have not assessed left ventricular performance for sudden death risk stratification in syncope.

Purpose of the Study:

  • To determine the impact of left ventricular dysfunction on sudden death risk.
  • To evaluate risk in patients with cardiac or unexplained syncope after electrophysiologic testing.

Main Methods:

  • Retrospective evaluation of 88 syncope patients undergoing electrophysiologic testing.
  • Analysis of left ventricular ejection fraction (LVEF) in relation to sudden death prognosis.
  • Logistic regression to identify independent predictors of cardiac syncope.

Related Experiment Videos

Main Results:

  • Mean LVEF was 0.41 +/- 0.20; 75% had structural heart disease.
  • A cardiac cause was found in 56% of patients; 44% had unexplained syncope.
  • Eight of nine sudden deaths (89%) occurred in patients with LVEF < 0.30.

Conclusions:

  • Left ventricular dysfunction is a critical factor in sudden death risk stratification for syncope.
  • Reduced LVEF (<0.30) strongly predicts adverse outcomes in cardiac syncope.
  • Further research is needed to optimize diagnostic and therapeutic strategies for syncope in this population.