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Pharmacological bridge to cardiac transplantation: current limitations
D Y Loisance1, P H Deleuze, R Houel
1Centre de Recherches Chirurgicales, CHU Henri Mondor, Faculté de Médicine, Creteil, France.
The Annals of Thoracic Surgery
|January 1, 1993
Abstract:
Addition of intravenous enoximone to sympathomimetic agents permits a rapid and drastic improvement in the clinical and hemodynamical condition of patients in cardiogenic shock referred for a mechanical bridge to transplantation. The present experience, based on the management of 52 patients, permits us to point out the current limitations of this pharmacological bridge: the rate of sudden death, the incompleteness of the physical rehabilitation of the patients, and the vanishing effect of intravenous enoximone.