Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lior-serotype variants in Campylobacter isolates from the same stool sample

B Zöllner1, H H Wuthe

  • 1Institut für Medizinische Mikrobiologie, Kiel, Germany.

Journal of Medical Microbiology
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[A rare tympanic lesion - paracentesis led to an interesting diagnosis].

Laryngo- rhino- otologie·2018
Same author

Aymptomatic CMV viremia is associated with increased levels of serum amyloid A in patients with advanced HIV-infection.

European journal of medical research·2008
Same author

Prevalence, incidence, and clinical relevance of the reverse transcriptase V207I mutation outside the YMDD motif of the hepatitis B virus polymerase during lamivudine therapy.

Journal of clinical microbiology·2005
Same author

Fatal influenza A infection with Staphylococcus aureus superinfection in a 49-year-old woman presenting as sudden death.

International journal of legal medicine·2004
Same author

[Hepatitis C. Virology, transmission modes, clinical aspects, prevention and therapy].

Der Anaesthesist·2002
Same author

Prevalence of SENV-H viraemia among healthy subjects and individuals at risk for parenterally transmitted diseases in Germany.

Journal of viral hepatitis·2002

Multiple Campylobacter strains with different heat-labile (Lior) serotypes can exist in a single stool sample. This variation may occur in vivo, particularly in Campylobacter coli strains with specific heat-stable (Lauwers) serotypes.

Area of Science:

  • Microbiology
  • Bacterial Pathogenesis
  • Molecular Typing

Background:

  • Campylobacter species are significant causes of bacterial gastroenteritis worldwide.
  • Accurate strain characterization is crucial for epidemiological studies and understanding transmission dynamics.
  • Heat-labile and heat-stable serotyping are key methods for differentiating Campylobacter isolates.

Purpose of the Study:

  • To investigate the occurrence and characteristics of multiple Campylobacter strains within single stool samples.
  • To determine if variations in heat-labile serotypes correlate with specific heat-stable serotypes or biochemical profiles.
  • To explore the potential for in vivo antigenic variation in Campylobacter.

Main Methods:

  • Isolation and characterization of Campylobacter strains from human stool samples.

Related Experiment Videos

  • Determination of biochemical properties for each isolate.
  • Serotyping using heat-labile (Lior) and heat-stable (Lauwers) antigen systems.

    • Main Results:

    • In 6 out of 60 infected stools, multiple Campylobacter strains with differing Lior-serotypes were identified.
    • In 4 of these cases, strains with different Lior-serotypes shared identical biochemical reactions and heat-stable antigenic patterns.
    • Campylobacter coli was identified in 76.5% of samples, with specific Lauwers antigens (O:3, O:14, O:16) found in isolates from three of the six multi-strain samples.

    Conclusions:

    • The presence of multiple Lior-serotypes within a single stool sample suggests potential in vivo antigenic variation.
    • This variation may be linked to specific heat-stable serotypes, particularly within Campylobacter coli.
    • Further research is warranted to elucidate the mechanisms and implications of Campylobacter antigenic diversity in vivo.