Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Factor VII assays

T E Hayes1, J Pike, R P Tracy

  • 1Department of Pathology, University of Vermont College of Medicine, Burlington.

Archives of Pathology & Laboratory Medicine
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advanced Practice Nurse Perceptions of Spirituality: A Global Quantitative Perspective in Everyday Life and Practice Settings.

Journal of holistic nursing : official journal of the American Holistic Nurses' Association·2025
Same author

Correction: The association of leptin and incident hypertension in the reasons for geographic and racial differences in stroke (REGARDS) cohort.

Journal of human hypertension·2024
Same author

The association of leptin and incident hypertension in the reasons for geographic and racial differences in stroke (REGARDS) cohort.

Journal of human hypertension·2024
Same author

Transcutaneous electrical nerve stimulation improves fatigue performance of the treated and contralateral knee extensors.

European journal of applied physiology·2019
Same author

Biochemical markers of bone turnover and risk of incident hip fracture in older women: the Cardiovascular Health Study.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2019
Same author

Correction.

Journal of medical economics·2019
Same journal

Assessing Human Epidermal Growth Factor Receptor 2 in Urothelial Carcinoma: Insights From Clinical Practice Into Scoring Criteria, Histologic Subtypes, and Genomic Characteristics Across Disease Sites.

Archives of pathology & laboratory medicine·2026
Same journal

Cross-Reactivity of TPIT Antibody Clone OTI2G1 in Chordoma: Structural Mechanisms and Diagnostic Implications.

Archives of pathology & laboratory medicine·2026
Same journal

Paracoccidioidomycosis at Autopsy: A Case Series and Literature Review.

Archives of pathology & laboratory medicine·2026
Same journal

Accuracy of Cytology Diagnosis for Well Differentiated Neuroendocrine Tumors: Assessment by the College of American Pathologists Non-Gynecologic Slide Program.

Archives of pathology & laboratory medicine·2026
Same journal

Serum Immunofixation Electrophoresis Guidance Conflict: A Call to Harmonize.

Archives of pathology & laboratory medicine·2026
Same journal

In Reply.

Archives of pathology & laboratory medicine·2026
See all related articles

Elevated coagulation factor VII levels are linked to cardiovascular disease. Standardizing assays and understanding factor VII forms are crucial for accurate risk assessment.

Area of Science:

  • Biochemistry
  • Cardiology
  • Clinical Chemistry

Background:

  • Prospective and cross-sectional studies suggest a link between elevated coagulation factor VII (FVII) and cardiovascular disease (CVD).
  • Current methods for assessing FVII levels, primarily the one-stage factor assay, lack standardization.
  • The presence of multiple forms of FVII in plasma and their impact on assay results are not fully understood.

Purpose of the Study:

  • To review the association between coagulation factor VII levels and cardiovascular disease.
  • To highlight the variability in methods used for assessing factor VII levels.
  • To identify areas for future research in standardizing factor VII assays and understanding its role in CVD.

Main Methods:

  • Review of existing prospective and cross-sectional studies.

Related Experiment Videos

  • Analysis of the common one-stage factor assay and its inherent variables.
  • Discussion of the potential impact of different factor VII forms on assay outcomes.

    • Main Results:

    • An association between elevated FVII and CVD is proposed by multiple studies.
    • Significant variability exists in the methodologies employed for FVII level assessment.
    • The contribution of different FVII forms to assay results is currently unknown.

    Conclusions:

    • Standardization of factor VII assays is needed for reliable CVD risk assessment.
    • Further research should focus on understanding the different forms of factor VII and their clinical significance.
    • Identifying non-FVII components affecting assays may reveal novel CVD risk indicators.