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Pustular psoriasis

E M Farber1, L Nall

  • 1Psoriasis Research Institute, Palo Alto, California 94301.

Cutis
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Pustular psoriasis presents in localized or generalized forms, triggered by factors like drugs and infections. Management focuses on eliminating triggers and employing targeted therapies for localized cases or systemic treatments for severe, life-threatening presentations.

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Area of Science:

  • Dermatology
  • Immunology

Background:

  • Pustular psoriasis is a rare, distinct subtype of psoriasis.
  • It manifests as either chronic localized pustular psoriasis or severe generalized pustular psoriasis.

Purpose of the Study:

  • To outline the clinical presentation and precipitating factors of pustular psoriasis.
  • To discuss management strategies for both localized and generalized forms.

Main Methods:

  • Literature review of pustular psoriasis.
  • Analysis of precipitating factors and treatment modalities.

Main Results:

  • Common triggers include medications (lithium, hydrochloroquine), topical irritants, infections, pregnancy, and UV exposure.
  • Infantile and juvenile forms are rare.

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  • Localized pustular psoriasis can be managed with short-contact anthralin or topical psoralen/ultraviolet A.
  • Severe cases may require systemic treatments like methotrexate, cyclosporin A, or corticosteroids.

    • Conclusions:

    • Identifying and eliminating precipitating factors is the primary management step.
    • Treatment selection depends on the form and severity of pustular psoriasis.