Genetic toxicology testing requirements: official and unofficial views from Europe

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Testing strategies in mutagenicity and genetic toxicology: an appraisal of the guidelines of the European Scientific Committee for Cosmetics and Non-Food Products for the evaluation of hair dyes.

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Genetic toxicology testing requirements: official and unofficial views from Europe

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The mutagenicity and carcinogenicity of hair dyes.

Regulatory aspects of genotoxicity testing: from hazard identification to risk assessment.

In vitro approaches to develop weight of evidence (WoE) and mode of action (MoA) discussions with positive in vitro genotoxicity results.

Testing strategies in mutagenicity and genetic toxicology: an appraisal of the guidelines of the European Scientific Committee for Cosmetics and Non-Food Products for the evaluation of hair dyes.

Interpretation of the biological relevance of genotoxicity test results: the importance of thresholds.

Recommendations for spacing of test chemical concentrations in the mouse lymphoma tk mutation assay (MLA)

Parental Tetracycline Exposure Induces Genotoxic Damage and Fitness Deficits in Daphnia magna Offspring.

Bergamot Leaf Extract Is Associated With Reduced Hepatic DNA Strand Breaks in Diet-Induced Obese Rats.

Mechanisms of PARP Inhibitor Resistance: From Replication Gap Biology and Transcription-Replication Conflicts to PROTAC-Based Next-Generation Strategies.

Conserved Active Site Loop Residues of E. coli DinB and Human DNA Polymerase Kappa Govern Activity.

Investigation of Ethylene Oxide Genotoxicity Dose-Response to Inform Cancer Risk Assessment.

Evaluating the Suitability of HepaRG Cells for Regulatory Micronucleus Testing: Comparing Results for a Diverse Set of 28 Chemicals to Regulatory Accepted TK6 Cells.

Development of the Japanese version of the work-life integration scale: Focusing on the work environment in Japan.

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Genetic toxicology testing requirements: official and unofficial views from Europe

Abstract:

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