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Neuropathies associated with diabetes

M A Ross1

  • 1Department of Neurology, University of Iowa College of Medicine, Iowa City.

The Medical Clinics of North America
|January 1, 1993
PubMed
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Diabetic neuropathy, a common diabetes complication, causes pain and autonomic issues. While the exact cause is unknown, metabolic and ischemic factors contribute, with symptom improvement possible through glycemic control.

Area of Science:

  • Neurology
  • Endocrinology
  • Diabetology

Background:

  • Diabetic neuropathy is the most common complication of diabetes and a leading cause of polyneuropathy.
  • It manifests as distal symmetric sensory polyneuropathy, often accompanied by bothersome pain.
  • Autonomic neuropathy is also frequent, leading to issues like postural hypotension and gastroparesis.

Purpose of the Study:

  • To review the diverse clinical presentations of diabetic neuropathy.
  • To discuss the potential causes, including metabolic and ischemic factors.
  • To highlight the importance of physician familiarity with less common forms.

Main Methods:

  • Review of existing literature on diabetic neuropathy.
  • Analysis of clinical manifestations and potential etiologies.

Related Experiment Videos

  • Discussion of current therapeutic approaches.

    • Main Results:

    • Diabetic neuropathy presents with sensory and autonomic symptoms.
    • Both metabolic and ischemic nerve injury are implicated in its pathogenesis.
    • Less common forms can mimic other neurological conditions.

    Conclusions:

    • Effective treatment to cure diabetic neuropathy is lacking.
    • Glycemic control and symptomatic therapy can lead to improvement.
    • Physicians must recognize the varied presentations of diabetic neuropathy.