Trichodysplasia and amelogenesis imperfecta

This paper describes a family in which members of two generations have an X-linked type of enamel dysplasia. All affected persons have symmetric pits in the cuticles of their hair shafts. The observation of these concurrent traits raises questions about the classification of amelogenesis imperfecta and the value of microscopic studies of the hair in the persons with purported isolated enamel dysplasias.