Eyelid involvement in acanthosis nigricans
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Updated: Nov 7, 2026

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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
E B Groos1, M J Mannis, T B Brumley
1Department of Ophthalmology, University of California, Davis 95618.
American Journal of Ophthalmology
|January 1, 1993
Abstract:
We treated a 56-year-old man who had acanthosis nigricans associated with gastric adenocarcinoma and involving the axillae, hands, feet, anus, soft palate, and eyes. The patient developed epiphora from occlusion of the canaliculi with papillomatous lesions. Recognition of the ocular signs of this paraneoplastic syndrome may indicate to the ophthalmologist that the patient should have a thorough oncologic examination.
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