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Solitary fibrous tumor
J G Batsakis1, R D Hybels, A K el-Naggar
1Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston 77030.
The Annals of Otology, Rhinology, and Laryngology
|January 1, 1993
Summary
Solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms. In the upper airway, sinonasal and nasopharyngeal SFTs are typically benign and manageable with surgical removal.
Area of Science:
- Oncology
- Pathology
- Otorhinolaryngology
Background:
- Solitary fibrous tumors (SFTs) were initially identified as pleural neoplasms.
- SFTs are mesenchymal neoplasms with both benign and malignant potential.
- Diagnosis requires excluding other soft tissue tumors.
Purpose of the Study:
- To review the characteristics of solitary fibrous tumors in the sinonasal and nasopharyngeal regions.
- To assess the clinical behavior and treatment outcomes of these extrapleural SFTs.
Main Methods:
- Histopathologic review of sinonasal and nasopharyngeal tumors.
- Exclusionary diagnosis to confirm SFTs.
- Analysis of clinical data for eight reported cases.
Main Results:
- Eight cases of SFTs in the sinonasal and nasopharyngeal areas were identified.
- None of the reported tumors exhibited malignant histological or biological features.
- Surgical excision was effective in managing these tumors.
Conclusions:
- Solitary fibrous tumors in the sinonasal and nasopharyngeal regions are predominantly benign.
- Complete surgical resection is an effective treatment strategy.
- Further research may clarify the behavior of SFTs in these specific locations.