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Injectable soft tissue substitutes

M Spira1, T Rosen

  • 1Division of Plastic Surgery, Baylor College of Medicine, Houston, Texas.

Clinics in Plastic Surgery
|January 1, 1993
PubMed
Summary
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Researchers reviewed injectable soft tissue substitutes, including nonbiologic and biologic options. The ongoing search for ideal injectable materials for tissue augmentation continues, focusing on safety and longevity.

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Plastic Surgery

Background:

  • Injectable soft tissue substitutes are crucial for aesthetic and reconstructive procedures.
  • Historically, various materials have been explored, with limitations in safety, efficacy, and duration.
  • The demand for improved injectable fillers persists in clinical practice.

Purpose of the Study:

  • To review historical and contemporary advancements in injectable soft tissue substitutes.
  • To describe nonbiologic alloplastic and biologic injectable materials.
  • To delineate the authors' and others' experiences with current materials, indications, and techniques.

Main Methods:

  • Comprehensive literature review of injectable soft tissue substitute development.

Related Experiment Videos

  • Categorization of injectables into nonbiologic alloplastic and biologic types.
  • Analysis of clinical applications, specific indications, and specialized techniques for available materials.

    • Main Results:

    • Overview of the evolution of injectable soft tissue substitute technology.
    • Description of the characteristics and applications of both nonbiologic and biologic injectables.
    • Synthesis of practical experiences and challenges associated with current materials.

    Conclusions:

    • The development of injectable soft tissue substitutes has progressed significantly.
    • Current materials offer various options but still present limitations.
    • The quest for an ideal injectable soft tissue substitute that is safe, effective, easy to use, and long-lasting remains a key objective.