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[Lung function disorders in Sjögren's syndrome]

O Scherak, G Schernthaner, H Ludwig

    Zeitschrift Fur Rheumatologie
    |January 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

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    Pulmonary function tests reveal significant lung impairment in patients with Sjögren

    Area of Science:

    • Pulmonary Medicine
    • Rheumatology
    • Immunology

    Context:

    • Sjögren's Syndrome (SS) is an autoimmune disorder often co-occurring with rheumatoid arthritis (RA).
    • Patients with SS frequently exhibit sicca symptoms alongside RA.
    • Lung involvement in SS is a recognized but not fully understood complication.

    Purpose:

    • To assess pulmonary function in patients with Sjögren's Syndrome.
    • To compare lung function abnormalities in SS with those typically seen in RA.
    • To investigate potential causes of lung function impairment in SS.

    Summary:

    • Pulmonary function tests were conducted on 15 patients with Sjögren's Syndrome, all of whom also had rheumatoid arthritis and sicca syndrome.
    • Abnormalities were noted in mean values for residual volume, compliance, and diffusion capacity.

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  • Vital capacity, residual volume, compliance, and diffusion capacity were abnormal in 40%, 46%, 60%, and 66% of patients, respectively.
  • Lung function impairment appeared more severe in SS than in RA, with potential contributions from progressive fibrosis.

    • Impact:

    • Highlights the significant impact of Sjögren's Syndrome on lung function.
    • Suggests that progressive fibrosis may exacerbate lung impairment in SS.
    • Underscores the need for pulmonary monitoring in patients with SS and RA.