Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Duchenne muscular dystrophy: MR grading system with functional correlation

G C Liu1, Y J Jong, C H Chiang

  • 1Department of Radiology, Chong-Ho Memorial Hospital, Kaohsiung Medical College, Taiwan, Republic of China.

Radiology
|February 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Black Hole Spectroscopy and Tests of General Relativity with GW250114.

Physical review letters·2026
Same author

GW250114: Testing Hawking's Area Law and the Kerr Nature of Black Holes.

Physical review letters·2025
Same author

[Establishment of a prognostic nomogram and discussion on optimal treatment for cervical adenocarcinoma:a retrospective study based on SEER database and Chinese single-center data].

Zhonghua fu chan ke za zhi·2024
Same author

[Association between abnormal oral glucose tolerance test patterns in the second trimester and large for gestational age newborns].

Zhonghua fu chan ke za zhi·2024
Same author

[Research progress on physiological changes caused by wearing N95 mask in patients with chronic obstruction pulmonary disease].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases·2022
Same author

Constraints on Cosmic Strings Using Data from the Third Advanced LIGO-Virgo Observing Run.

Physical review letters·2021

Magnetic resonance (MR) imaging effectively assesses Duchenne muscular dystrophy (DMD) progression by evaluating muscle changes. This MR grading system correlates with clinical status and can aid in monitoring disease severity.

Area of Science:

  • Neurology
  • Medical Imaging
  • Musculoskeletal Diseases

Background:

  • Duchenne muscular dystrophy (DMD) is a progressive genetic disorder affecting muscles.
  • Accurate assessment of disease progression is crucial for patient management.

Purpose of the Study:

  • To evaluate the utility of magnetic resonance (MR) imaging in assessing Duchenne muscular dystrophy (DMD).
  • To develop and validate an MR grading system for DMD progression.

Main Methods:

  • MR imaging of pelvic girdle, thigh, and calf muscles in 29 DMD patients.
  • Development of an MR grading system assessing preserved muscles, fatty infiltration, and subcutaneous fat.
  • Correlation analysis between MR grade, clinical grade, disease duration, age, and creatine kinase levels.

Related Experiment Videos

Main Results:

  • Gracilis, sartorius, semitendinous, and semimembranous muscles showed relative resistance to DMD.
  • MR grade correlated significantly with clinical functional grade, disease duration, and patient age.
  • MR imaging identified disease severity in patients with low clinical grades and showed progression in follow-up studies.

Conclusions:

  • MR imaging is a valuable tool for assessing DMD severity and progression.
  • The developed MR grading system aids in monitoring disease and may assist in prebiopsy mapping.