Thrombogenic intracranial vasculitis in tuberculous meningitis. A 20 year "post mortem" survey

The pathological features of twenty-three cases of tuberculous meningitis, examined over a twenty year period are reported. Ten cases, diagnosed clinically, were treated; thirteen undiagnosed cases were not treated. Phlebitis was found in twenty-two and arteritis of varying degrees in twenty. Tuberculous thrombophebitis was observed in eight cases and haemorrhagic infarction was present in ten. One case showed thrombosis in the territory of the mid-cerebral artery with ipsilateral white infarction; four presented white infarctions which were attributed to end- or panarteritic changes. previous descriptions of intracranial tuberculous thrombosis are briefly reviewed. Possible consequences of this vasculitis are mentioned.