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Updated: Aug 23, 2026

Listeria monocytogenes Infection of the Brain
Published on: October 2, 2018
[Neurological complications of infectious mononucleosis (author's transl)]
Abstract:
The authors report three different and rare forms of neurological complication associated with infectious mononucleosis. The first two, which are faily unusual in their clinical signs, occurred during the course of two typical cases of mononucleosis, one in the form of progressively regressive myelitis and the other in that of amyotrophic paralysis of the shoulder. The third occurred in isolation, after an encephalitic attack combined with a state of epileptic mal, with no other accompanying infectious sign. On the basis of these three single cases, and recent data in the literature about the Epstein-Barr virus, the authors briefly recapitulate the neurological clinical forms of infectious monouncleosis and the means of serological diagnosis; they discuss the frequency and pathogeny of these complications and tentatively suggest certain similarities with other nervous disorders observed in the course of proliferative or dysglobulinaemic diseases.
Insights
Infectious mononucleosis can cause rare neurological complications, including myelitis, shoulder paralysis, and epilepsy. Research explores these rare neurological manifestations and their link to Epstein-Barr virus.
Area of Science:
- Neurology
- Infectious Diseases
- Virology
Background:
- Infectious mononucleosis, commonly known as mono, is a viral illness often associated with fatigue and fever.
- Neurological complications, though rare, can occur during the course of infectious mononucleosis.
Observation:
- The study details three rare neurological complications: a case of myelitis, a case of amyotrophic paralysis of the shoulder, and a case of encephalitis with epilepsy.
- These cases highlight the diverse and unusual neurological presentations associated with Epstein-Barr virus infection.
Findings:
- The authors present three distinct neurological syndromes linked to infectious mononucleosis.
- These include myelitis, shoulder paralysis, and isolated encephalitis with seizures, emphasizing the varied clinical spectrum.
Implications:
- The findings prompt a review of neurological manifestations of infectious mononucleosis and diagnostic methods.
- Further research into the pathogenesis of these neurological complications and potential links to other systemic diseases is suggested.
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