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The inherent DNase of pyocin AP41 causes breakdown of chromosomal DNA
1Department of Molecular Biology, Mitsubishi Kasei Institute of Life Sciences, Tokyo, Japan.
Journal of Bacteriology
|February 1, 1993
Abstract:
Pyocin AP41 degrades the chromosomal DNA in sensitive strains of Pseudomonas aeruginosa but has little effect on RNA, protein, and lipid syntheses. In vitro experiments showed that the carboxyl-terminal part of the large subunit of pyocin AP41 carries an inherent DNase that is responsible for its killing action.