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Pathological fracture in haemoglobinopathy: treatment by irradiation
C Papavasiliou1, G Kotoulas, A Layiandreou
1University of Athens, Department of Radiology, Areteion Hospital, Greece.
Abstract:
A patient suffering from thalassaemia, with extreme osteoporosis, coarse trabeculation and cortical thinning of the bones, developed a pathological fracture of the left hip. This was treated by a single dose of radiotherapy. It is suggested that the radiotherapy facilitated the healing process by eliminating the causative factor of the fracture, which was the expanding and over-proliferating bone marrow.