Molecular cloning of cDNA encoding the phenol/aryl form of sulfotransferase (mSTp1) from mouse liver

The cDNA sequence of the mouse liver phenol/aryl form of sulfotransferase (mSTp1) has been determined. The cloned cDNA consists of 1269 base pairs (bp) and contains an 897 nucleotide open reading frame (ORF) beginning at nucleotide 65, which encodes a 298 amino acid polypeptide of 34.7 kDa. Alignment of mSTp1 to other sulfotransferases shows overall identities of 87% to r-STp, 37% to r-STa, 48% to r-STe, 51% to b-STe, and 37% to h-STa, at the deduced amino acid level.