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Structure of an antimutagen from Carmona retusa leaves
I M Villaseñor1, D A Edu, J B Bremner
1Institute of Chemistry, University of the Philippines, Quezon City.
Carcinogenesis
|January 1, 1993
Abstract:
An antimutagenic compound was isolated from the leaves of Carmona retusa (Vahl) Masam. Its structure has been elucidated by spectral analysis to be 4-hydroxy-7,8,11,12,15,7',8',11',12',15'-decahydro-beta, psi-carotene. The results of the Micronucleus Test, an in vivo method, showed that the isolated antimutagenic compound reduced by approximately 68.4% the number of micronucleated polychromatic erythrocytes induced by tetracycline, a known mutagen.