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Graded exercise testing in patients with sinus node dysfunction

J A Abbott, D S Hirschfeld, F W Kunkel

    The American Journal of Medicine
    |March 1, 1977
    PubMed
    Summary
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    Patients with sinus node dysfunction have reduced exercise capacity due to arrhythmias or heart failure. Atropine did not improve maximal heart rate or oxygen uptake during maximal exercise.

    Area of Science:

    • Cardiology
    • Exercise Physiology

    Background:

    • Sinus node dysfunction (SND) affects heart rate regulation.
    • Patients with SND often experience reduced exercise tolerance.

    Purpose of the Study:

    • To assess exercise capacity in patients with SND.
    • To evaluate the effect of atropine on exercise parameters in SND patients.

    Main Methods:

    • Maximal upright graded bicycle stress testing.
    • Serial measurements of heart rate and oxygen uptake.
    • Intravenous atropine administration in most patients.

    Main Results:

    • SND patients achieved lower maximal heart rates and oxygen uptakes than controls.
    • Atropine did not significantly alter maximal exercise capacity.

    Related Experiment Videos

  • Pacemaker use did not significantly impact maximal oxygen uptake.

    • Conclusions:

    • Physically active SND patients have diminished exercise capacity.
    • Contributing factors include cardiac arrhythmias, heart failure, and autonomic dysfunction.