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Malignant melanoma in children

K Chun1, M Vázquez, J L Sánchez

  • 1Department of Dermatology, University of Puerto Rico School of Medicine, San Juan 00936-5067.

International Journal of Dermatology
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

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Malignant melanoma in children is rare but can be aggressive. Congenital nevi are a risk factor, but routine excision in early childhood is not recommended due to low risk before puberty.

Area of Science:

  • Pediatric Oncology
  • Dermatology
  • Cancer Epidemiology

Background:

  • Malignant melanoma is uncommon in prepubertal children, though risk factors may appear in childhood.
  • Congenital melanocytic nevi are recognized risk factors for melanoma development.

Purpose of the Study:

  • To investigate the incidence and characteristics of malignant melanoma in children and adolescents in Puerto Rico.
  • To evaluate the association between congenital nevi and pediatric melanoma.

Main Methods:

  • Retrospective study of pediatric melanoma cases (up to 16 years) from the Puerto Rico Cancer Registry (1973-1990).
  • Analysis of case demographics, clinical presentation, and outcomes.

Main Results:

  • Seven cases of pediatric melanoma were identified, representing 0.94% of total melanomas.

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  • Three cases (43%) developed in children with a history of small congenital melanocytic nevus.
  • Melanoma in children can exhibit aggressive behavior, with varying Clark's levels of invasion.

    • Conclusions:

    • Pediatric malignant melanoma, though rare, can be aggressive.
    • While congenital nevi are a risk factor, routine excision in early childhood is not supported by current evidence.
    • Observation of small congenital nevi in childhood with potential excision around puberty is a logical approach.