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Related Experiment Videos

Behavioral perimetry in monkeys

R S Harwerth1, E L Smith, L DeSantis

  • 1College of Optometry, University of Houston, Texas 77204-6052.

Investigative Ophthalmology & Visual Science
|January 1, 1993
PubMed
Summary
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Monkey and human visual fields are similar, allowing computerized perimetry for studying ocular disorders in non-human primates. This enables advanced research into vision and disease progression.

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Comparative Vision Research

Background:

  • Normative visual sensitivity data across retinal eccentricity is crucial for static perimetry analysis.
  • Assessing visual field changes in patients could extend to monkeys with ocular disorders if their visual fields are comparable to humans.

Purpose of the Study:

  • To compare normal visual field data between rhesus monkeys and human subjects.
  • To determine if standard computerized perimetry techniques are applicable to monkeys for ocular disorder research.

Main Methods:

  • Utilized the Humphrey Field Analyzer's standard threshold programs.
  • Collected and compared normal visual field data from three rhesus monkeys and eight human subjects.

Main Results:

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  • Monkeys demonstrated excellent behavioral control during testing, with reliable data.
  • Monkey visual fields showed comparable sensitivity to stimulus size, Statpac global indices, and threshold variance to human visual fields.

Conclusions:

  • The visual fields of rhesus monkeys and humans are significantly similar.
  • Computerized perimetry techniques can be applied to monkey subjects with minimal modifications for research purposes.