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Related Concept Videos

Autoregulation of Blood Flow01:17

Autoregulation of Blood Flow

Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.
Pressure Variation in a Fluid at Rest01:11

Pressure Variation in a Fluid at Rest

In a fluid at rest, the pressure at any point beneath the fluid surface depends solely on the depth, not on the container's shape or size. This principle, known as hydrostatic pressure, arises because, in stationary fluids, there is no acceleration, meaning the forces within the fluid balance out. Only vertical forces, caused by the weight of the fluid above, contribute to pressure changes with depth.
When measuring pressure at two different levels within the fluid, the difference in pressure...
Steady, Laminar Flow Between Parallel Plates01:17

Steady, Laminar Flow Between Parallel Plates

Understanding steady, laminar flow between parallel plates is essential for analyzing and designing flow in narrow rectangular channels, commonly found in various water conveyance and drainage systems. The Navier-Stokes equations govern fluid motion and are generally challenging to solve due to their nonlinearity. However, simplifications are possible in certain cases, like the steady laminar flow between parallel plates. For this scenario, we assume steady, incompressible, laminar flow.
Steady, Laminar Flow in Circular Tubes01:23

Steady, Laminar Flow in Circular Tubes

Hagen-Poiseuille flow describes a viscous fluid's steady, incompressible flow through a cylindrical tube with a constant radius R. This flow profile is often applied to understand fluid transport in narrow channels, such as capillaries. It serves as a foundational example of laminar flow. In this model, cylindrical coordinates (r,θ,z) are used to describe the radial (r), angular (θ), and axial (z) dimensions within the tube. For Hagen-Poiseuille flow, the velocity profile is purely axial,...

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Related Experiment Video

Updated: Jul 25, 2026

Characterization of the Isolated, Ventilated, and Instrumented Mouse Lung Perfused with Pulsatile Flow
10:02

Characterization of the Isolated, Ventilated, and Instrumented Mouse Lung Perfused with Pulsatile Flow

Published on: April 29, 2011

Arterial barostasis along the mouse tail between different steady-state flows

R M Reinecke

    The American Journal of Physiology
    |February 1, 1977
    PubMed
    Summary

    Barostasis, or pressure homeostasis in the vascular system, was observed in mouse tails. Despite a measurable pressure drop, flow increased significantly with a slight temperature rise, indicating effective regulation.

    Area of Science:

    • Physiology
    • Vascular Biology

    Background:

    • Barostasis refers to homeostasis concerning pressure within the vascular system.
    • Understanding local pressure and flow regulation is crucial in physiology.

    Purpose of the Study:

    • To investigate barostasis in the mouse tail.
    • To measure arterial pressure and flow at different temperatures.

    Main Methods:

    • Utilized pneumatic cuffs and plethysmographs to measure pressure and flow.
    • Experiments conducted on unanesthetized mice tails at 20 and 25 degrees C.

    Main Results:

    • A measurable pressure decrease was observed from proximal to distal regions of the tail.
    • Between 20 and 25 degrees C, barostasis was evident with minimal proportional pressure change and significant flow increase.

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    Published on: April 29, 2011

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  • Circulatory occlusion was followed by a transient increase in flow.

    • Conclusions:

    • The mouse tail exhibits barostatic mechanisms.
    • Temperature influences vascular pressure and flow regulation.