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Related Experiment Videos

Sellar susceptibility artifacts: theory and implications

A D Elster1

  • 1Department of Radiology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27157-1022.

AJNR. American Journal of Neuroradiology
|January 1, 1993
PubMed
Summary

A focal susceptibility artifact, larger than 1 mm2, was observed in 14% of pituitary MRI scans. This artifact near the sellar floor can mimic or obscure pituitary microadenomas.

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Area of Science:

  • Radiology
  • Medical Imaging
  • Electromagnetism

Background:

  • Susceptibility artifacts on MRI can complicate image interpretation.
  • The pituitary gland is a critical endocrine structure.
  • Accurate visualization of the pituitary is essential for diagnosing hormonal disorders.

Purpose of the Study:

  • To determine the prevalence of a specific MR susceptibility artifact in the pituitary gland.
  • To investigate the physical basis and characteristics of this artifact.
  • To understand how this artifact may affect the diagnosis of pituitary pathology.

Main Methods:

  • Review of coronal, T1-weighted MR images of 50 healthy subjects' pituitary glands.
  • Construction of a plexiglass phantom to replicate the artifact in vitro.
  • Systematic variation of readout gradient direction and intensity to study artifact appearance.

Main Results:

  • A focal susceptibility artifact (>1 mm2) was found in 14% of subjects.
  • The artifact was located within the pituitary gland, near the sellar floor-sphenoidal septum junction.
  • Artifact magnitude correlated linearly with readout gradient strength and direction; phantom reproduction was successful.

Conclusions:

  • A focal susceptibility artifact is identifiable on pituitary MR imaging.
  • This artifact commonly occurs near the sellar floor and sphenoidal septum.
  • The artifact can mimic or obscure pituitary microadenomas, impacting clinical diagnosis.

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