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Vasculitis presenting as primary leptomeningeal enhancement with minimal parenchymal findings
1Department of Diagnostic Radiology, School of Medicine, Yale University, New Haven, CT 06510.
Abstract:
In this case of biopsy-proved granulomatous angiitis, MR showed prominent leptomeningeal enhancement with comparatively little parenchymal involvement. Pathologically, granulomatous angiitis chiefly affects small vessels, with a predilection for those in the leptomeninges. Although marked leptomeningeal enhancement is not the most common finding, vasculitis should be added to the differential diagnosis of this MR appearance.
Insights
Granulomatous angiitis can present with prominent leptomeningeal enhancement on MRI, even with minimal brain involvement. This finding suggests vasculitis should be considered in the differential diagnosis for such imaging results.
Area of Science:
- Neurology
- Radiology
- Pathology
Background:
- Granulomatous angiitis is a rare condition affecting small blood vessels.
- It predominantly impacts the leptomeningeal vessels.