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Intraocular lymphoma invades the optic nerve and orbit
S Noda1, S Hayasaka, T Setogawa
1Department of Ophthalmology, Shimane Medical University, Izumo, Japan.
Annals of Ophthalmology
|January 1, 1993
Summary
This case study highlights a rare instance of intraocular lymphoma with orbital invasion in a 54-year-old woman. Despite initial uveitis diagnosis, malignant lymphoma was confirmed, leading to widespread disease and eventual death.
Area of Science:
- Ophthalmology
- Oncology
- Pathology
Background:
- A 54-year-old woman presented with ocular inflammation (uveitis) resistant to corticosteroid treatment.
- The condition progressed to involve both eyes within a year, with initial diagnostic tests proving inconclusive.
Observation:
- Computed tomographic scanning revealed orbital invasion in the right eye.
- Histopathological examination of an orbital biopsy confirmed malignant lymphoma.
Findings:
- The patient received radiotherapy and chemotherapy, which reduced the orbital mass and intraocular lesions.
- A subsequent brain tumor was diagnosed and treated, but the patient died at age 57.
Implications:
- This case underscores the importance of considering rare conditions like intraocular lymphoma in complex ophthalmic presentations.
- Early and accurate diagnosis is crucial for effective management of orbital and intraocular lymphomas.