Intraocular lymphoma invades the optic nerve and orbit

A diagnosis uveitis OS was made in a 54-year-old woman; this was resistant to corticosteroid treatment. One year later, both eyes were involved. Examination of the vitreous aspirate and the results of a chorioretinal biopsy OD did not yield a correct diagnosis. Computed tomographic scanning showed orbital invasion OD. Malignant lymphoma was diagnosed after a biopsy specimen of the orbital contents was studied histopathologically. Radiotherapy and chemotherapy diminished the orbital mass and intraocular lesions. After regression of the orbital lesion, a brain tumor was found and treated with radiotherapy and chemotherapy. At age 57 years, the patient died. We believe that our patient had a rare case of intraocular lymphoma associated with orbital invasion.