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Cutaneous vasculitis and IgA glomerulonephritis in ankylosing spondylitis
C Beauvais1, G Kaplan, B Mougenot
1Department of Rheumatology, Hôpital Saint Antoine, Paris, France.
Annals of the Rheumatic Diseases
|January 1, 1993
Abstract:
Two patients with ankylosing spondylitis were found to have IgA nephropathy and leucocytoclastic cutaneous vasculitis. Immunofluorescence showed perivascular deposition of IgA in the skin of one patient and in the mesangium of both patients. Such an association has been reported only once before. This supports the concept of abnormal IgA immune stimulation in the pathogenesis of ankylosing spondylitis.