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Erythropoietin. Biology and clinical applications
1Bone Marrow Transplantation Program, George Washington University School of Medicine, Washington, DC.
Archives of Internal Medicine
|February 8, 1993
Abstract:
Hemopoiesis is a complex process that underlies the production of highly specialized cells. The mechanisms involved in this process include positive and negative feedback by humoral activities, pluripotent stem cell self-renewal and differentiation, and local interactions between stromal components of the hemopoietic microenvironment and various stem and progenitor cells.