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Effect of Schistosoma mansoni infection on pentobarbital-induced sleeping-time in mice

P M Coelho, A C Freire, F G Araujo

The American Journal of Tropical Medicine and Hygiene

|January 1, 1977

Abstract:

The sleeping-time induced by sodium pentobarbital is greatly increased in mice experimentally infected with Schistosoma mansoni. The degree of hypnosis is affected by the female worm burden, probably because the hepatic lesions produced by schistosome eggs cause slow metabolisation of anesthetics.

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