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Prostaglandin prophylaxis and bladder function after vaginal hysterectomy: a prospective randomised study
A Bergman1, Y Mushket, D Gordon
1University of Southern California School of Medicine, Women's Hospital, Los Angeles 90033.
Objective:
To assess the efficacy of prostaglandins in enhancing bladder function after vaginal hysterectomy.
Design:
Prospective randomised study of women who underwent vaginal hysterectomy between November 1989 and August 1990.
Setting:
Sackler School of Medicine Tel Aviv University Medical Center, Department of Obstetrics and Gynaecology 'B'.
Subjects:
24 women who underwent vaginal hysterectomy and anterior and posterior colporrhaphy for prolapse.
Intervention:
Administration of prostaglandin F2 alpha 5 mg intravesically or E2 3 mg intravaginally versus 100 ml saline intravesically (control) daily, starting on the first postoperative day, until adequate spontaneous voiding was established.
Results:
Women receiving PGE2 resumed spontaneous bladder functions earlier, required significantly fewer days catheterisation and had significantly less febrile morbidity compared to women in the control group or PGE2 group.
Conclusions:
Prostaglandins PGE2 intravaginally are beneficial in enhancing functions after vaginal hysterectomy [corrected].