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Related Experiment Videos

Autotransfusion in aortic surgery: the Haemocell System 350 cell saver

M Kalra1, M J Beech, H al-Khaffaf

  • 1Department of Surgery, University Hospital of South Manchester, UK.

The British Journal of Surgery
|January 1, 1993
PubMed
Summary
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The Haemocell System 350 effectively salvaged 60% of blood loss during abdominal aortic surgery, preserving cellular components and showing no adverse effects. This autotransfusion device is easy to use and requires no specialized operator.

Area of Science:

  • Cardiovascular Surgery
  • Biomedical Engineering
  • Hematology

Background:

  • Autotransfusion is a valuable technique for reducing allogeneic blood transfusions.
  • Newer devices aim to improve the efficiency and safety of intraoperative blood salvage.
  • The Haemocell System 350 represents a novel approach to cell separation for autotransfusion.

Purpose of the Study:

  • To evaluate the efficacy and safety of the Haemocell System 350 for intraoperative autotransfusion.
  • To assess the quality of salvaged blood components.
  • To monitor for any adverse effects of the autotransfusion process.

Main Methods:

  • Autotransfusion using the Haemocell System 350 during elective abdominal aortic reconstruction in 10 patients.
  • Measurement of salvaged blood volume and autotransfused volume.

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  • Analysis of cellular component preservation (including platelets).
  • Assessment of coagulation parameters, plasma hemoglobin, and heparin levels.
  • Evaluation of oxyhemoglobin dissociation curves and organ function.

    • Main Results:

    • A mean of 60% of total blood loss was salvaged.
    • Good preservation of cellular components, including platelets, was observed.
    • No coagulopathy or significant adverse effects were noted.
    • Slightly elevated plasma hemoglobin and negligible heparin levels were recorded post-surgery.
    • Transient drops in fibrinogen and low concentrations of fibrin degradation products were seen.
    • Salvaged red blood cells demonstrated normal oxygen affinity.
    • Renal and hepatic function remained unaltered.

    Conclusions:

    • The Haemocell System 350 is an effective and safe device for intraoperative autotransfusion.
    • It allows for significant blood salvage with good preservation of cellular components.
    • The device is user-friendly and does not require a specialized operator, making it suitable for clinical use.