Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Oncogenes in prostate cancer. An update

D M Peehl1

  • 1Department of Urology, Stanford University School of Medicine, CA 94305-5118.

Cancer
|February 1, 1993
PubMed
Summary

Oncogenes are linked to many cancers, but their role in prostate cancer remains unclear. Further research is needed to identify specific oncogenes driving prostate cancer development.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Suramin, hydrocortisone, and retinoic acid modify inhibitory effects of 1,25-dihydroxyvitamin D(3) on prostatic epithelial cells.

Urologic oncology·2011
Same author

Recent advances in the development of animal and cell culture models for prostate cancer research A minireview.

Urologic oncology·2011
Same author

Human prostatic epithelial and stromal cell lines and strains.

Urologic oncology·2011
Same author

Basic science of hormonal therapy for prostate cancer.

Reviews in urology·2006
Same author

Tumor-suppression function of transcription factor USF2 in prostate carcinogenesis.

Oncogene·2005
Same author

Tumor-selective killing by selenite in patient-matched pairs of normal and malignant prostate cells.

The Prostate·2005

Area of Science:

  • Oncology
  • Molecular Biology
  • Cancer Genetics

Background:

  • Oncogenes are crucial in various human cancers, sometimes offering diagnostic or prognostic value.
  • Currently, no specific oncogene is definitively linked to prostate cancer initiation or progression.
  • Previous investigations into ras oncogenes in prostate cancer showed no significant role.

Purpose of the Study:

  • To review the current understanding of oncogene involvement in prostate cancer.
  • To highlight the need for further investigation into potential oncogenes in prostate cancer development.

Main Methods:

  • Literature review of studies on oncogenes and prostate cancer.
  • Analysis of existing research on ras, myc, and sis oncogenes in relation to prostate cancer.
  • Evaluation of suggested roles for growth factors and receptors.

Main Results:

  • The ras oncogene does not appear to be significantly involved in prostate cancer development.
  • Limited studies suggested myc and sis oncogene involvement, but require further validation.
  • The oncogenic role of growth factors or their receptors in prostate cancer is not well-established.

Conclusions:

  • Despite the established role of oncogenes in other cancers, their specific involvement in prostate cancer is yet to be conclusively identified.
  • Intensive and focused research is necessary to uncover the oncogenes that drive prostate cancer.

Related Experiment Videos