Related Experiment Video
Updated: Aug 10, 2026
A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Conservative approaches to the management of localized prostatic cancer
1Department of Urology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021.
Background:
The management of early stage prostatic cancer is controversial.
Methods:
Pertinent literature concerning the conservative management of early stage prostatic cancer by early endocrine therapy (EET) or by deferred treatment (DT) was reviewed.
Results:
EET has not been systematically studied. Available evidence suggests that early stage prostatic cancer often progresses slowly and that DT results in a cancer-specific mortality of approximately 80% at 10 years.
Conclusions:
EET warrants clinical investigation. DT is a management option, at least in patients with a life expectancy of 10 years or less.
