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Value of delayed hypersensitivity index in patients with malignancy
Annals of Allergy
|March 1, 1977
Summary
A delayed hypersensitivity index, a measure of cellular immunity, can be assessed using in vivo testing with recall antigens and DNCB. This index is a valuable dynamic indicator for various medical conditions, including malignancy.
Area of Science:
- Immunology
- Cellular Immunity Assessment
Background:
- Cellular immunity plays a crucial role in host defense.
- Assessing cellular immunity is vital for managing various medical conditions.
Purpose of the Study:
- To introduce a standardized method for obtaining a delayed hypersensitivity index.
- To highlight the utility of this index as a dynamic indicator of cellular immunity.
Main Methods:
- Standardized in vivo testing utilizing available antigens.
- Employing recall antigens and DNCB (dinitrochlorobenzene) to evaluate the afferent limb of the immune response.
Main Results:
- A reliable delayed hypersensitivity index can be obtained through the described in vivo testing.
- The index serves as a valid indicator of cellular immune function.
Conclusions:
- The delayed hypersensitivity index is a practical and valid measure of cellular immunity.
- This index is important for monitoring patients with malignancy and other medical conditions.