Recurrent malignant melanoma following a 35-year disease-free interval

A case is presented of recurrent melanoma following a 35-year disease-free interval after treatment for stage I disease. Although the case seems to indicate a recurrence of melanoma, the possibility that the "recurrent lesions" may have been a new primary lesion should be considered. Regardless of disease-free interval following initial treatment, a complete cure of the disease can never be assumed.