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Related Experiment Videos

Quantitative velocity images from thick slab 2D phase contrast

D M Weber1, Y Wang, F R Korosec

  • 1Department of Medical Physics, University of Wisconsin-Madison.

Magnetic Resonance in Medicine
|February 1, 1993
PubMed
Summary

This study introduces a new two-dimensional phase contrast (2D PC) angiography method to retain quantitative velocity data in thick slab acquisitions. The technique accounts for intravoxel phase cancellation, improving blood flow velocity measurements in vessels.

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Area of Science:

  • Medical Imaging
  • Cardiovascular Imaging
  • Magnetic Resonance Imaging

Background:

  • Thick slab two-dimensional phase contrast (2D PC) angiography offers rapid anatomical imaging.
  • Standard 2D PC angiography sacrifices quantitative velocity data due to projection dephasing gradients.
  • Accurate velocity quantification requires addressing intravoxel phase cancellation in thick slab acquisitions.

Purpose of the Study:

  • To present a novel 2D PC acquisition scheme for preserving quantitative velocity information in thick slab imaging.
  • To describe a method for calculating mean velocity in vessels with laminar flow using the new scheme.
  • To evaluate the impact of intravoxel phase cancellation on velocity measurements.

Main Methods:

  • Developed a modified 2D PC acquisition sequence for thick slab imaging.

Related Experiment Videos

  • Implemented a method to correct for intravoxel phase cancellation in velocity measurements.
  • Analyzed data from acquisitions simulating laminar flow within a vessel.

    • Main Results:

    • The proposed 2D PC scheme successfully retains quantitative velocity information in thick slab acquisitions.
    • A method for determining mean velocity, accounting for intravoxel phase cancellation, was outlined.
    • Ignoring intravoxel phase cancellation led to a 10% overestimation of true mean velocity.

    Conclusions:

    • The new 2D PC acquisition scheme enables accurate quantitative velocity measurements from thick slab images.
    • Accounting for intravoxel phase cancellation is crucial for precise blood flow velocity assessment.
    • This technique enhances the utility of thick slab 2D PC angiography for cardiovascular flow analysis.