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Extraskeletal mesenchymal chondrosarcoma

L G Shapeero1, D Vanel, D Couanet

  • 1Department of Radiology, Institut Gustave-Roussy, Villejuif, France.

Radiology
|March 1, 1993
PubMed
Summary
This summary is machine-generated.

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Extraskeletal mesenchymal chondrosarcoma (EMC) imaging in children and adults shows distinct patterns. While adult EMC has a poor prognosis, pediatric cases demonstrate better outcomes, highlighting potential differences in disease behavior.

Area of Science:

  • Radiology
  • Oncology
  • Pathology

Background:

  • Extraskeletal mesenchymal chondrosarcoma (EMC) is a rare soft-tissue tumor.
  • Understanding its imaging characteristics is crucial for diagnosis and prognosis.

Purpose of the Study:

  • To describe the imaging findings of extraskeletal mesenchymal chondrosarcoma (EMC) in pediatric and adult patients.
  • To correlate imaging features with clinical outcomes.

Main Methods:

  • Retrospective analysis of seven patients (3 children, 4 adults) with pathologically confirmed EMC.
  • Review of conventional radiography, tomography, computed tomography (CT), and magnetic resonance (MR) imaging.
  • Correlation of imaging findings with clinical data, including treatment response and survival.

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Main Results:

  • EMC presented as a soft-tissue mass with characteristic calcifications (ring, arc, stippled) on radiography and CT.
  • Contrast-enhanced CT revealed lobulation and peripheral enhancement with central low-attenuation areas.
  • MR imaging showed lobulated masses with high T2 signal intensity and contrast enhancement with low-signal foci.
  • Adult patients experienced recurrences and metastases, leading to mortality.
  • Pediatric patients had better prognoses, with two disease-free survivors and one death from leukemia secondary to chemotherapy.

Conclusions:

  • Imaging features of EMC, including chondroid-type calcifications and specific enhancement patterns, may reflect its biphasic histopathology.
  • Prognosis differs significantly between pediatric and adult patients with EMC.
  • Early and accurate diagnosis through advanced imaging is vital for appropriate management and improved outcomes.