Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chemosurgery for melanoma

F E Mohs

    Archives of Dermatology
    |March 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Chemosurgery offers a microscopically controlled method for melanoma excision, ensuring complete tumor eradication. This technique achieved a 50% five-year cure rate in 86 determinate cases, including advanced melanomas.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Penicillin ointment-impregnated gauze in the local treatment of infections.

    Archives of surgery (Chicago, Ill. : 1920)·2010
    Same author

    Chemosurgical treatment of cancer of the nose; a microscopically controlled method.

    Archives of surgery (Chicago, Ill. : 1920)·2010
    Same author

    Chemosurgical treatment of cancer of the face; a microscopically controlled method of excision.

    Archives of dermatology and syphilology·2010
    Same author

    Chemosurgical treatment of cancer of the ear; a microscopically controlled method of excision.

    Surgery·2010
    Same author

    Oral malignant melanoma treated with Mohs micrographic surgery by fixed-tissue technique.

    Archives of otolaryngology--head & neck surgery·1998
    Same author

    Cutaneous malignant melanoma treated by Mohs surgery. Review of the treatment results of 179 cases from the Mohs Melanoma Registry.

    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·1997

    Area of Science:

    • Oncology
    • Dermatology
    • Surgical Pathology

    Background:

    • Melanoma treatment requires complete tumor eradication to prevent recurrence.
    • Standard surgical excision may leave microscopic disease, leading to treatment failure.
    • Chemosurgery offers a method for precise tumor margin control.

    Observation:

    • This study evaluated a modified chemosurgical technique for melanoma excision.
    • The technique involves in situ chemical fixation and an extended margin after microscopic clearance.
    • 103 consecutive melanoma cases were analyzed, with 86 determinate cases for five-year follow-up.

    Findings:

    • The chemosurgical method demonstrated a 50% five-year cure rate in determinate cases.
    • This rate is notable given that 69% of cases were nodular melanomas and 64% invaded subcutaneous tissues (Clark's level 5).

    Related Experiment Videos

  • The modified chemosurgery effectively addressed unsuspected outgrowths and potential lymphatic spread.

    • Implications:

    • Microscopically controlled chemosurgery is a viable and effective treatment for various melanoma types.
    • The technique's ability to achieve complete eradication improves patient outcomes, especially for advanced melanomas.
    • Further research into optimizing chemosurgical protocols for melanoma is warranted.