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Preparation of autologous fibrin glue from pericardial blood
H K Kjaergard1, U S Weis-Fogh, J J Thiis
1Department of Cardiothoracic Surgery, Rigshospitalet, Copenhagen, Denmark.
The Annals of Thoracic Surgery
|February 1, 1993
Abstract:
To salvage patients' blood and improve hemostasis in cardiac operations, autologous fibrin glue was prepared in a new way by means of ethanol from pericardial blood. The yield from 44 mL of blood was 2.1 +/- 0.7 mL (mean +/- standard deviation) of fibrinogen concentrate with a concentration of 25.1 +/- 7.5 mg/mL; 2.7 mL of two-component glue was obtained after the addition of thrombin solution. The glue has the advantages of safety from transmission of viral diseases and from immunologic reactions.