Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ceftriaxone-induced acute pancreatitis

A E Zimmermann1, B G Katona, J S Jodhka

  • 1Department of Pharmacy, Harbor Hospital Center, Baltimore, MD 21230.

The Annals of Pharmacotherapy
|January 1, 1993
PubMed
Summary

Ceftriaxone, an antibiotic, may cause acute pancreatitis. A patient with short-bowel syndrome developed pancreatitis after receiving ceftriaxone, with symptoms resolving after discontinuation, suggesting a probable drug-induced adverse effect.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to "Socioeconomic status moderates associations between CNS serotonin and expression of beta2-integrins CD11b and CD11c" [J. Psychiatr Res. (2010) 44:373-377].

Journal of psychiatric research·2019
Same author

A prepared mind--Ernest Edward Tyzzer's legacy of research into avian diseases.

Avian diseases·2014
Same author

Syphilis, Hepatitis, and Pancreatitis: Is the Uncommon Becoming Common in the HIV(+) Patient?

Case reports in infectious diseases·2014
Same author

Tularemia; first case to be reported in Alaska.

Public health reports (Washington, D.C. : 1896)·2010
Same author

Epidemiological studies of coccidiosis in the domesticated fowl (Gallus gallus): IV. reciprocity between the immune status of floor-reared chickens and their excretion of oocysts.

Applied parasitology·2010
Same author

Epidemiological studies of coccidiosis in the domesticated fowl (Gallus gallus):III. The influence of the fowl's defaecation pattern on the excretion patterns of Eimeria tenella and E acervulina oocysts.

Applied parasitology·2010

Area of Science:

  • Gastroenterology
  • Pharmacology
  • Clinical Medicine

Background:

  • Short-bowel syndrome (SBS) patients often require home total parenteral nutrition (TPN).
  • Catheter-related bloodstream infections (CRBSI) are a common complication in TPN-dependent patients.
  • Antibiotic therapy is crucial for managing sepsis in immunocompromised individuals.

Observation:

  • A TPN-dependent SBS patient developed gram-negative catheter sepsis.
  • The patient was treated with intravenous ceftriaxone for sepsis.
  • Following ceftriaxone initiation, the patient presented with symptoms of acute pancreatitis.

Findings:

  • The patient exhibited elevated lipase and amylase levels, jaundice, and abdominal pain.
  • Discontinuation of ceftriaxone led to the resolution of pancreatitis symptoms.

Related Experiment Videos

  • No other causative factors for pancreatitis were identified.

    • Implications:

    • Ceftriaxone is a potential cause of drug-induced acute pancreatitis.
    • Clinicians should consider ceftriaxone when evaluating patients with acute pancreatitis.
    • Further research is needed to elucidate the mechanism of ceftriaxone-induced pancreatitis.