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Updated: Aug 12, 2026

Quantification of Orofacial Phenotypes in Xenopus
Published on: November 6, 2014
A comparison of computer versus panel assessment of two groups of patients with cleft lip and palate
J K Laitung1, B A Coghlan, R W Pigott
1Department of Plastic Surgery, Frenchay Hospital, Bristol.
Abstract:
A computer-based system of assessing asymmetry was used to compare standardised photographs of primarily corrected cleft noses, uncorrected cleft noses and control (normal) noses. A significant difference was found between control and cleft groups for both upper nasal perimeter (p < 0.001) and nostril outline (p = 0.001), and between uncorrected and corrected noses for upper nasal perimeter (p = 0.03) but not for nostril outline (p = 0.99). Comparing the results achieved by panel assessment (Cussons et al., 1992) with this of the same patients revealed some discordance related to the influence of extraneous factors on panel decisions. Panel assessment is needed in the evaluation of overall appearance, whilst the computer method is able to assess the results of different techniques, and from different centres, on specific features where symmetry is a major objective of surgical technique.

